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Assistant Professor Astrid Sasse

Pharmaceutical Chemistry


Peer Reviewed

Dul M, Paluch KJ, Kelly H, Healy AM, Sasse A, Tajber L. Self-assembled carrageenan/protamine polyelectrolyte nanoplexes-Investigation of critical parameters governing their formation and characteristics., Carbohydr Polym. 123, 2015, p339-349.

Micallef, S., Stark, H., Sasse, A., Polymorphisms and genetic linkage of histamine receptors., Life sciences, 93, (15), 2013, p487-494

Sasse, A., Histamine H4R Ligand Database, Inflammation Research, 42nd Annual Meeting of the European Histamine Reserach Society (EHRS), Lodz, Poland, 8-11th May 2013, 62, (1), Springer, 2013, ppS7 - S7

Fabio Boylan, Astrid Sasse, Helen Sheridan(ed.), Holistic Approaches to Health Maintenance in the BSc. Pharmacy Degree at Trinity College, Institute of Technology, Dundalk, Ireland, 19-20th June 2013, 2013
Notes: [CSSI - Confederation of Student Services in Ireland]

Micallef, S., Quinn, E., Morris, D., Sasse, A., MICROSATELLITE REPEAT EXPANSIONS IN HUMAN HISTAMINE(4) RECEPTOR GENE, Inflammation Research, 41st Annual Meeting of the European Histamine Research Society (EHRS), Belfast, Northern Ireland, UK, 2-5th May 2012, 61, (2), Springer, 2012, ppS52 - S52

Micallef, S., Quinn, E., Morris, D., Sasse, A., Genetic Polymorphism in Human Histamine 4 Receptor Gene and Schizophrenia, Society for Neuroscience Annual Meeting, Washington DC, USA, 12-16th Nov 2011, 2011, pp259

Multiple Steps in the Blockade of Exocytosis by Botulinum Neurotoxins in, editor(s)Jankovic, J., Albanese, A., Atassi, M.Z., Dolly, J.O., Hallett, M., Mayer N. , Botulinum Toxin - Therapeutic Clinical Practice and Science, Philadelphia, Saunders Elsevier, 2009, pp1 - 14, [Dolly, J.O., Meng, J., Wang, J., Lawrence, G.W., Boedeker, M., Zurawski, T.H., Sasse, A.]

Meng, J., Ovsepian, S.V., Wang, J., Pickering, M., Sasse, A., Aoki, K.R., Lawrence, G.W., Dolly, J.O., Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti-nociceptive potential., The Journal of neuroscience : the official journal of the Society for Neuroscience, 29, (15), 2009, p4981 - 4992

Wang, J., Meng, J., Lawrence, G.W., Zurawski, T.H., Sasse, A., Bodeker, M.O., Gilmore, M.A., Fernández-Salas, E., Francis, J., Steward, L.E., Aoki, K.R., Dolly, J.O., Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics., The Journal of biological chemistry, 283, (25), 2008, p16993 - 17002

Weiss, C., Sametsky, E., Sasse, A., Spiess, J., Disterhoft, J.F., Acute stress facilitates trace eyeblink conditioning in C57BL/6 male mice and increases the excitability of their CA1 pyramidal neurons., Learning & memory (Cold Spring Harbor, N.Y.), 12, (2), 2005, p138 - 143

Tezval, H., Jahn, O., Todorovic, C., Sasse, A., Eckart, K., Spiess, J., Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model., Proceedings of the National Academy of Sciences of the United States of America, 101, (25), 2004, p9468 - 9473

Sasse, A., Ligneau, X., Rouleau, A., Elz, S., Ganellin, C.R., Arrang, J.M., Schwartz, J.C., Schunack, W., Stark, H., Influence of bulky substituents on histamine h(3) receptor agonist/antagonist properties., Journal of medicinal chemistry, 45, (18), 2002

Nickel, T., Bauer, U., Schlicker, E., Kathmann, M., Göthert, M., Sasse, A., Stark, H., Schunack, W., Novel histamine H(3)-receptor antagonists and partial agonists with a non-aminergic structure., British journal of pharmacology, 132, (8), 2001

Sasse, A., Ligneau, X., Sadek, B., Elz, S., Pertz, H.H., Ganellin, C.R., Arrang, J.M., Schwartz, J.C., Schunack, W., Stark, H., Benzophenone derivatives and related compounds as potent histamine H3-receptor antagonists and potential PET/SPECT ligands., Archiv der Pharmazie, 334, (2), 2001

Sasse, A., Schunack, W., Stark, H., Separation of chiral 4-substituted imidazole derivatives by cyclodextrin-modified capillary electrophoresis., Biomedical chromatography : BMC, 15, (1), 2001

Morisset, S., Sasse, A., Gbahou, F., Héron, A., Ligneau, X., Tardivel-Lacombe, J., Schwartz, J.C., Arrang, J.M., The rat H3 receptor: gene organization and multiple isoforms., Biochemical and biophysical research communications, 280, (1), 2001

Kiec-Kononowicz, K., Wiecek, M., Sasse, A., Ligneau, X., Elz, S., Ganellin, C.R., Schwartz, J.C., Stark, H., Schunack, W., Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity., Die Pharmazie, 55, (5), 2000

Sasse, A., Sadek, B., Ligneau, X., Elz, S., Pertz, H.H., Luger, P., Ganellin, C.R., Arrang, J.M., Schwartz, J.C., Schunack, W., Stark, H., New histamine H(3)-receptor ligands of the proxifan series: imoproxifan and other selective antagonists with high oral in vivo potency., Journal of medicinal chemistry, 43, (17), 2000

Sasse, A., Stark, H., Ligneau, X., Elz, S., Reidemeister, S., Ganellin, C.R., Schwartz, J.C., Schunack, W., (Partial) agonist/antagonist properties of novel diarylalkyl carbamates on histamine H3 receptors., Bioorganic & medicinal chemistry, 8, (5), 2000

Sasse, A., Stark, H., Reidemeister, S., Hüls, A., Elz, S., Ligneau, X., Ganellin, C.R., Schwartz, J.C., Schunack, W., Novel partial agonists for the histamine H(3) receptor with high in vitro and in vivo activity., Journal of medicinal chemistry, 42, (20), 1999

Sasse, A., Kiec-Kononowicz, K., Stark, H., Motyl, M., Reidemeister, S., Ganellin, C.R., Ligneau, X., Schwartz, J.C., Schunack, W., Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity., Journal of medicinal chemistry, 42, (4), 1999

Non Peer Reviewed

The Histamine H3 Receptor: Gene Organization, Multiple Isoforms, Constitutive Activity and Molecular Pharmacology in, editor(s)Watanabe, T., Timmerman, H., Yanai, K. , Histamine Research in the New Millennium, Elsevier Science, 2001, pp9 - 21, [Arrang, J.-M., Morisset, S., Rouleau, A., Tarvidel-Lacombe, J., Gbahou, F., Ligneau, X., Héron, A., Sasse, A., Stark, H., Schunack, W., Ganellin, C.R., Schwartz, J.-C., ]

Partial Agonists for the Histamine H3 Receptor with High in Vivo Activity in, editor(s)Watanabe, T., Timmerman, H., Yanai, K. , Histamine Research in the New Millennium, Elsevier Science, 2001, pp77 - 82, [Schunack, W., Sasse, A., Stark, H., Elz, S., Ligneau, X., Ganellin, C.R., Schwartz, J.-C]